Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection

We present further study of a subset of carbapenems, arising from a previously reported machine learning approach, with regard to their mouse pharmacokinetic profiling and subsequent study in a mouse model of sub-acute Mycobacterium tuberculosis infection. Pharmacokinetic metrics for such small mole...

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Udgivet i:PLoS One
Main Authors: Jadhav, Ravindra, Gallardo-Macias, Ricardo, Kumar, Gaurav, Daher, Samer S., Kaushik, Amit, Bigelow, Kristina M., Nuermberger, Eric L., Lamichhane, Gyanu, Freundlich, Joel S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092647/
https://ncbi.nlm.nih.gov/pubmed/33939697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249841
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