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Shortened tethering filaments stabilize presynaptic vesicles in support of elevated release probability during LTP in rat hippocampus

Long-term potentiation (LTP) is a cellular mechanism of learning and memory that results in a sustained increase in the probability of vesicular release of neurotransmitter. However, previous work in hippocampal area CA1 of the adult rat revealed that the total number of vesicles per synapse decreas...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Jung, Jae Hoon, Kirk, Lyndsey M., Bourne, Jennifer N., Harris, Kristen M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092591/
https://ncbi.nlm.nih.gov/pubmed/33875591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018653118
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