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Electrical unfolding of cytochrome c during translocation through a nanopore constriction

Many small proteins move across cellular compartments through narrow pores. In order to thread a protein through a constriction, free energy must be overcome to either deform or completely unfold the protein. In principle, the diameter of the pore, along with the effective driving force for unfoldin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tripathi, Prabhat, Benabbas, Abdelkrim, Mehrafrooz, Behzad, Yamazaki, Hirohito, Aksimentiev, Aleksei, Champion, Paul M., Wanunu, Meni
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092471/
https://ncbi.nlm.nih.gov/pubmed/33883276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016262118
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