SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

The COVID-19 pandemic presents an urgent health crisis. Human neutralizing antibodies (hNAbs) that target the host ACE2 receptor-binding domain (RBD) of the SARS-CoV-2 spike(1–5) show therapeutic promise and are being evaluated clincally(6–8). To determine structural correlates of SARS-CoV-2 neutral...

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發表在:Nature
Main Authors: Barnes, Christopher O., Jette, Claudia A., Abernathy, Morgan E., Dam, Kim-Marie A., Esswein, Shannon R., Gristick, Harry B., Malyutin, Andrey G., Sharaf, Naima G., Huey-Tubman, Kathryn E., Lee, Yu E., Robbiani, Davide F., Nussenzweig, Michel C., West, Anthony P., Bjorkman, Pamela J.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092461/
https://ncbi.nlm.nih.gov/pubmed/33045718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2852-1
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