A pocket-factor–triggered conformational switch in the hepatitis B virus capsid

Viral hepatitis is growing into an epidemic illness, and it is urgent to neutralize the main culprit, hepatitis B virus (HBV), a small-enveloped retrotranscribing DNA virus. An intriguing observation in HB virion morphogenesis is that capsids with immature genomes are rarely enveloped and secreted....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lecoq, Lauriane, Wang, Shishan, Dujardin, Marie, Zimmermann, Peter, Schuster, Leonard, Fogeron, Marie-Laure, Briday, Mathilde, Schledorn, Maarten, Wiegand, Thomas, Cole, Laura, Montserret, Roland, Bressanelli, Stéphane, Meier, Beat H., Nassal, Michael, Böckmann, Anja
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092406/
https://ncbi.nlm.nih.gov/pubmed/33879615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022464118
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