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The Penicillin-Binding Protein PbpP Is a Sensor of β-Lactams and Is Required for Activation of the Extracytoplasmic Function σ Factor σ(P) in Bacillus thuringiensis

β-Lactams are a class of antibiotics that target the synthesis of peptidoglycan, an essential component of the cell wall. β-Lactams inhibit the function of penicillin-binding proteins (PBPs), which form the cross-links between strands of peptidoglycan. Resistance to β-lactams complicates the treatme...

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Vydáno v:mBio
Hlavní autoři: Nauta, Kelsie M., Ho, Theresa D., Ellermeier, Craig D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092216/
https://ncbi.nlm.nih.gov/pubmed/33758089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00179-21
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