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The roles and regulation of MDM2 and MDMX: it is not just about p53

Most well studied as proteins that restrain the p53 tumor suppressor protein, MDM2 and MDMX have rich lives outside of their relationship to p53. There is much to learn about how these two proteins are regulated and how they can function in cells that lack p53. Regulation of MDM2 and MDMX, which tak...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Klein, Alyssa M., de Queiroz, Rafaela Muniz, Venkatesh, Divya, Prives, Carol
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091979/
https://ncbi.nlm.nih.gov/pubmed/33888565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.347872.120
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