Cell spheroids are as effective as single cells suspensions in the treatment of critical-sized bone defects

BACKGROUND: Due to their multilineage potential and high proliferation rate, mesenchymal stem cells (MSC) indicate a sufficient alternative in regenerative medicine. In comparison to the commonly used 2-dimensional culturing method, culturing cells as spheroids stimulates the cell-cell communication...

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Veröffentlicht in:BMC Musculoskelet Disord
Hauptverfasser: Findeisen, Lisa, Bolte, Julia, Vater, Corina, Petzold, Cathleen, Quade, Mandy, Müller, Lars, Goodman, Stuart B., Zwingenberger, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091496/
https://ncbi.nlm.nih.gov/pubmed/33941144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-021-04264-y
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