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Exome Sequencing Identifies Abnormalities in Glycosylation and ANKRD36C in Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura

BACKGROUND: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal blood disorder, resulting from autoantibodies against ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13). However, the mechanism underlying anti-ADAMTS13 autoantibo...

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Bibliografiske detaljer
Udgivet i:Thromb Haemost
Main Authors: Basu, Malay Kumar, Massicano, Felipe, Yu, Lijia, Halkidis, Konstantine, Pillai, Vikram, Cao, Wenjing, Zheng, Liang, Zheng, X. Long
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091491/
https://ncbi.nlm.nih.gov/pubmed/33184803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1719030
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