Broadly Reactive Human Monoclonal Antibodies Targeting the Pneumococcal Histidine Triad Protein Protect against Fatal Pneumococcal Infection

Streptococcus pneumoniae remains a leading cause of bacterial pneumonia despite the widespread use of vaccines. While vaccines are effective at reducing the incidence of most serotypes included in vaccines, a rise in infection due to nonvaccine serotypes and moderate efficacy against some vaccine se...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Huang, Jiachen, Gingerich, Aaron D., Royer, Fredejah, Paschall, Amy V., Pena-Briseno, Alma, Avci, Fikri Y., Mousa, Jarrod J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091081/
https://ncbi.nlm.nih.gov/pubmed/33649050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00747-20
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