Long-Term Control of Urinary Free Cortisol With Osilodrostat in Patients With Cushing’s Disease: Final Results From the LINC 2 Study

Introduction: During the 22-week core LINC 2 study, the oral 11β-hydroxylase inhibitor osilodrostat normalized mean urinary free cortisol (mUFC) in 79% (15/19) of patients with Cushing’s disease. This report describes long-term LINC 2 efficacy and safety results following an optional extension. Meth...

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Dettagli Bibliografici
Pubblicato in:J Endocr Soc
Autori principali: Fleseriu, Maria, Biller, Beverly M K, Bertherat, Jerome, Young, Jacques, Arnaldi, Giorgio, O’Connell, Paul, Izquierdo, Miguel, Pedroncelli, Alberto M, Pivonello, Rosario
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Neuroendocrinology and Pituitary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090717/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1063
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