Probiotic Supplementation with Lactobacillus plantarum 299v Lowers Systemic Inflammation, Reduces Islet ER Stress and Prevents Type 1 Diabetes in BioBreeding Rats

Type 1 diabetes (T1D) is an autoimmune disease characterized by destruction of the pancreatic β-cells. T1D pathogenesis has a strong genetic basis. However, in recent decades, the prevalence of high-risk HLA haplotypes among new diagnoses has declined, the age of onset has decreased, and T1D inciden...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Main Authors: Sargin, Pinar, Ciecko, Ashley E, Dew, Kristen, Rhonda, Geoffrey, Jia, Shuang, Laib, Tyler, Roethle, Mark F, Hessner, Martin J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
Assuntos:
Pediatric Endocrinology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090711/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1350
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