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Evaluation of Mayer-Rokitansky-Kuster-Hauser (MRKH) Patient Families by Whole Genome Sequencing

Introduction: MRKH is a characterized by the congenital absence of the uterus and vagina in 46,XX individuals. A subset of these patients also has associated renal, skeletal, cardiac and/or auditory defects. Familial cases suggest a genetic component, but to date only pathogenic variants in WNT4 and...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Dougherty, Michael P, Chorich, Lynn P, Layman, Lawrence Clarke
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090648/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1025
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