A Phase 2B, Open-Label, Dose-Ranging Study of Encaleret (CLTX-305) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)

Autosomal dominant hypocalcemia type 1 (ADH1) is a rare form of hypoparathyroidism caused by gain-of-function pathogenic variants in the gene encoding the calcium-sensing receptor (CaSR). It is characterized by variable degrees of hypocalcemia, hyperphosphatemia, and hypomagnesemia, with inappropria...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Gafni, Rachel Ilana, Hartley, Iris Ruth, Roszko, Kelly Lauter, Nemeth, Edward F, Pozo, Karen A, Sani-Grosso, Ramei, Sridhar, Ananth, Fox, Jonathan C, Collins, Michael T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Bone and Mineral Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089760/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.515
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