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Phosphoinositide 3-Kinase Inhibitor-Induced Hyperglycemia

Background: Phosphoinositide 3-kinase inhibitors (PI3Ki) are a new class of medications used to treat HR positive, HER2 negative, PIK3CA mutated advanced or metastatic breast cancer. Inhibition of PI3K, a key enzyme in the insulin signaling pathway, leads to disruption of glucose metabolism and freq...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Shey, Susan, Kim, Sarah, Kim, Julie, Murphy, Elizabeth J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089671/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.803
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