The 5-Phosphatase SHIP2 Promotes Neutrophil Chemotaxis and Recruitment

Neutrophils, the most abundant circulating leukocytes in humans have key roles in host defense and in the inflammatory response. Agonist-activated phosphoinositide 3-kinases (PI3Ks) are important regulators of many facets of neutrophil biology. PIP3 is subject to dephosphorylation by several 5’ phos...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Michael, Melina, McCormick, Barry, Anderson, Karen E., Karmakar, Utsa, Vermeren, Matthieu, Schurmans, Stéphane, Amour, Augustin, Vermeren, Sonja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089392/
https://ncbi.nlm.nih.gov/pubmed/33953730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.671756
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