Metformin Attenuates ROS via FOXO3 Activation in Immune Cells

Forkhead box O 3 (FOXO3) is a transcription factor involved in cell metabolism, inflammation and longevity. Here, we investigated if metformin can activate FOXO3 in human immune cells and affects the subsequent level of reactive oxygen/nitrogen species (ROS/RNS) in immune cells. AMP-activated protei...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Hartwig, Jelka, Loebel, Madlen, Steiner, Sophie, Bauer, Sandra, Karadeniz, Zehra, Roeger, Carsten, Skurk, Carsten, Scheibenbogen, Carmen, Sotzny, Franziska
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089390/
https://ncbi.nlm.nih.gov/pubmed/33953705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.581799
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