Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell Transplantation

Older patients with hematologic malignancies are increasingly considered for allogeneic hematopoietic cell transplantation with encouraging outcomes. While aging-related thymic dysfunction remains a major obstacle to optimal and timely immune reconstitution post- transplantation, recent accumulating...

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Pubblicato in:Front Immunol
Autori principali: Lin, Richard J., Elias, Harold K., van den Brink, Marcel R. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089387/
https://ncbi.nlm.nih.gov/pubmed/33953731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.674093
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