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Innate Immune Modulation Induced by EBV Lytic Infection Promotes Endothelial Cell Inflammation and Vascular Injury in Scleroderma

Microvascular injury is considered an initial event in the pathogenesis of scleroderma and endothelial cells are suspected of being the target of the autoimmune process seen in the disease. EBV has long been proposed as a trigger for autoimmune diseases, including scleroderma. Nevertheless, its cont...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Farina, Antonella, Rosato, Edoardo, York, Michael, Gewurz, Benjamin E., Trojanowska, Maria, Farina, Giuseppina Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089375/
https://ncbi.nlm.nih.gov/pubmed/33953718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.651013
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