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Targeting SLC1A5 and SLC3A2/SLC7A5 as a Potential Strategy to Strengthen Anti-Tumor Immunity in the Tumor Microenvironment

Cancer cells are metabolically vigorous and are superior in the uptake of nutrients and in the release of the tumor microenvironment (TME)-specific metabolites. They create an acidic, hypoxic, and nutrient-depleted TME that makes it difficult for the cytotoxic immune cells to adapt to the metabolica...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Nachef, Marianna, Ali, Alaa Kassim, Almutairi, Saeedah Musaed, Lee, Seung-Hwan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089370/
https://ncbi.nlm.nih.gov/pubmed/33953707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.624324
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