Inhibition of ALDH1A1 Activity in Cisplatin-Resistant Ovarian Cancer Cells Alters Their Cancer Stemness, Cell Cycle Profile and Mitochondrial Respiration Rate

Introduction: Ovarian cancer is one of the leading cause of morbidity and death among women, with a five-year relative survival rate of only 30% in patients diagnosed with distant metastasis. The ovarian cancer cells initially respond to first-line platinum drug cisplatin [cis-diamminedichloroplatin...

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Detaylı Bibliyografya
Yayımlandı:J Endocr Soc
Asıl Yazarlar: Ramachandran, Ilangovan, Ramadoss, Sivakumar, Sen, Suvajit, Karuppaiyah, Selvendiran, Kumaran, R Ileng, Chaudhuri, Gautam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Tumor Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089254/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.2094
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