Severe Disease Activity and Liver Fibrosis Are Associated With a Lack of Hepatic Mitochondrial Adaptation in Patients With NASH

Dysfunctional mitochondrial function is believed to play a vital role in the progression of nonalcoholic steatohepatitis (NASH) to advanced fibrosis and cirrhosis. However, most evidence arises from animal models while there is limited data in humans. The characteristic histological finding of NASH...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Kalavalapalli, Srilaxmi, Barb, Diana, Leiva, Eddison Godinez, Lomonaco, Romina M, Fanous, Nada, Chug, Radhika, Friedman, Jeffrey, Rabe, Matthew, Cowan, Tyler M, Dillard, Rachel, Poulton, Danielle, Mansour, Lydia, Shrestha, Sulav, Cusi, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Adipose Tissue, Appetite, and Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089219/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.053
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