Early Exposure of Fosphenytoin, Levetiracetam and Valproic acid after High Dose Intravenous Administration in Young Children with Benzodiazepine-refractory Status Epilepticus

Fosphenytoin (FOS) and its active form, phenytoin (PHT), levetiracetam (LEV), and valproic acid (VPA) are commonly used second-line treatments of status epilepticus. However, limited information is available regarding LEV and VPA concentrations following high intravenous doses particularly in young...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Sathe, Abhishek G., Mishra, Usha, Ivaturi, Vijay, Brundage, Richard, Cloyd, James C., Elm, Jordan J., Chamberlain, James M., Silbergleit, Robert, Kapur, Jaideep, Lowenstein, Daniel H., Shinnar, Shlomo, Cock, Hannah R., Fountain, Nathan B., Babcock, Lynn, Coles, Lisa D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089035/
https://ncbi.nlm.nih.gov/pubmed/33336359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1801
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