Loading...
The PKM2 activator TEPP‐46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF‐1α accumulation
AIMS/INTRODUCTION: Tubulointerstitial fibrosis is a hallmark of diabetic nephropathy and is associated with an epithelial‐to‐mesenchymal transition (EMT) program and aberrant glycolysis. Dimeric pyruvate kinase (PK) M2 (PKM2) acts as a key protein kinase in aberrant glycolysis by promoting the accum...
Na minha lista:
| Udgivet i: | J Diabetes Investig |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8089020/ https://ncbi.nlm.nih.gov/pubmed/33314682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.13478 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|