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N‐glycosylated GPNMB ligand independently activates mutated EGFR signaling and promotes metastasis in NSCLC

Lung cancer is the leading cause of cancer‐related death worldwide. As well as the identified role of epidermal growth factor receptor (EGFR), its association with driver mutations has improved the therapeutics for patients with lung cancer harboring EGFR mutations. These patients usually display sh...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Han, Chia‐Li, Chen, Xuan‐Ren, Lan, Albert, Hsu, Yuan‐Ling, Wu, Pei‐Shan, Hung, Pei‐Fang, Hung, Chung‐Lieh, Pan, Szu‐Hua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088973/
https://ncbi.nlm.nih.gov/pubmed/33706413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14872
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