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N‐glycosylated GPNMB ligand independently activates mutated EGFR signaling and promotes metastasis in NSCLC

Lung cancer is the leading cause of cancer‐related death worldwide. As well as the identified role of epidermal growth factor receptor (EGFR), its association with driver mutations has improved the therapeutics for patients with lung cancer harboring EGFR mutations. These patients usually display sh...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Han, Chia‐Li, Chen, Xuan‐Ren, Lan, Albert, Hsu, Yuan‐Ling, Wu, Pei‐Shan, Hung, Pei‐Fang, Hung, Chung‐Lieh, Pan, Szu‐Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088973/
https://ncbi.nlm.nih.gov/pubmed/33706413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14872
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