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VISTA: A Mediator of Quiescence and a Promising Target in Cancer Immunotherapy

V-domain Ig suppressor of T cell activation (VISTA) is a B7 family member that maintains T cell and myeloid quiescence and is a promising target for combination cancer immunotherapy. During inflammatory challenges, VISTA activity reprograms macrophages towards reduced production of proinflammatory c...

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Bibliografiske detaljer
Udgivet i:Trends Immunol
Main Authors: Yuan, Long, Tatineni, Jahnavi, Mahoney, Kathleen M., Freeman, Gordon J.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088836/
https://ncbi.nlm.nih.gov/pubmed/33495077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2020.12.008
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