The Phosphatidyl-myo-Inositol Dimannoside Acyltransferase PatA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo

Mycobacterium tuberculosis comprises an unusual cell envelope dominated by unique lipids and glycans that provides a permeability barrier against hydrophilic drugs and is central for its survival and virulence. Phosphatidyl-myo-inositol mannosides (PIMs) are glycolipids considered to be not only key...

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Gepubliceerd in:J Bacteriol
Hoofdauteurs: Boldrin, Francesca, Anso, Itxaso, Alebouyeh, Sogol, Sevilla, Iker A., Geijo, Mariví, Garrido, Joseba M., Marina, Alberto, Mazzabò, Laura Cioetto, Segafreddo, Greta, Guerin, Marcelo E., Manganelli, Riccardo, Prados-Rosales, Rafael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088522/
https://ncbi.nlm.nih.gov/pubmed/33468587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00439-20
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