Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery

Obesity is a growing burden to health and the economy worldwide. Obesity is associated with central µ-opioid receptor (MOR) downregulation and disruption of the interaction between MOR and dopamine D(2) receptor (D(2)R) system in the ventral striatum. Weight loss recovers MOR function, but it remain...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Karlsson, Henry K., Tuominen, Lauri, Helin, Semi, Salminen, Paulina, Nuutila, Pirjo, Nummenmaa, Lauri
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088437/
https://ncbi.nlm.nih.gov/pubmed/33934103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01370-2
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