An Indole-2-Carboxamide Derivative, LG4, Alleviates Diabetic Kidney Disease Through Inhibiting MAPK-Mediated Inflammatory Responses

AIM: Elevated inflammatory signaling has been shown to play an important role in diabetic kidney disease (DKD). We previously developed a new anti-inflammatory compound LG4. In the present study, we have tested the hypothesis that LG4 could prevent DKD by suppressing inflammation and identified the...

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Bibliografiske detaljer
Udgivet i:J Inflamm Res
Main Authors: Qian, Jianchang, Yin, Sihui, Ye, Lin, Wang, Zhe, Shu, Sheng, Mou, Zhenxin, Xu, Mingjiang, Chattipakorn, Nipon, Liu, Zhiguo, Liang, Guang
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088301/
https://ncbi.nlm.nih.gov/pubmed/33948087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S308353
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