Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia

Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set daily rhythms in sinoatrial (SA) and atrioventricular (AV) node activity, and...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hayter, Edward A., Wehrens, Sophie M. T., Van Dongen, Hans P. A., Stangherlin, Alessandra, Gaddameedhi, Shobhan, Crooks, Elena, Barron, Nichola J., Venetucci, Luigi A., O’Neill, John S., Brown, Timothy M., Skene, Debra J., Trafford, Andrew W., Bechtold, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087694/
https://ncbi.nlm.nih.gov/pubmed/33931651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22788-8
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