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DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells

ADAMTS9 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family, and its expression is frequently silenced due to promoter hypermethylation in various human cancers. However, the underlying mechanisms remain largely unknown. In this study, we investigate...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sun, Weilin, Ma, Gang, Zhang, Li, Wang, Pengliang, Zhang, Nannan, Wu, Zizhen, Dong, Yinping, Cai, Fenglin, Chen, Liqiao, Liu, Huifang, liang, Han, Deng, Jingyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087691/
https://ncbi.nlm.nih.gov/pubmed/33931579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03628-5
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