Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients

Pathogenic mutations in fumarate hydratase (FH) drive hereditary leiomyomatosis and renal cell cancer (HLRCC) and increase the risk of developing uterine leiomyomas (ULMs). An integrated proteogenomic analysis of ULMs from HLRCC (n = 16; FH-mutation confirmed) and non-syndromic (NS) patients (n = 12...

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Pubblicato in:Sci Rep
Autori principali: Bateman, Nicholas W., Tarney, Christopher M., Abulez, Tamara, Soltis, Anthony R., Zhou, Ming, Conrads, Kelly, Litzi, Tracy, Oliver, Julie, Hood, Brian, Driggers, Paul, Viollet, Coralie, Dalgard, Clifton, Wilkerson, Matthew, Catherino, William, Hamilton, Chad A., Darcy, Kathleen M., Casablanca, Yovanni, Al-Hendy, Ayman, Segars, James, Conrads, Thomas P., Larry Maxwell, G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087684/
https://ncbi.nlm.nih.gov/pubmed/33931688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88585-x
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