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Synthetic single cell RNA sequencing data from small pilot studies using deep generative models

Deep generative models, such as variational autoencoders (VAEs) or deep Boltzmann machines (DBMs), can generate an arbitrary number of synthetic observations after being trained on an initial set of samples. This has mainly been investigated for imaging data but could also be useful for single-cell...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Treppner, Martin, Salas-Bastos, Adrián, Hess, Moritz, Lenz, Stefan, Vogel, Tanja, Binder, Harald
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087667/
https://ncbi.nlm.nih.gov/pubmed/33931726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88875-4
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