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Cholesterol and Cholesterol Bilayer Domains Inhibit Binding of Alpha-Crystallin to the Membranes Made of the Major Phospholipids of Eye Lens Fiber Cell Plasma Membranes

The concentration of α-crystallin decreases in the eye lens cytoplasm, with a corresponding increase in membrane-bound α-crystallin during cataract formation. The eye lens’s fiber cell plasma membrane consists of extremely high cholesterol (Chol) content, forming cholesterol bilayer domains (CBDs) w...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Timsina, Raju, Trossi-Torres, Geraline, O’Dell, Matthew, Khadka, Nawal K., Mainali, Laxman
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087645/
https://ncbi.nlm.nih.gov/pubmed/33744256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2021.108544
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