Effect of Immune Activation on the Kynurenine Pathway and Depression Symptoms – A Systematic Review and Meta-Analysis

Dysregulated kynurenine (KYN) pathway has been implicated in the pathophysiology of depression. In this systematic review, we examined the relationship between kynurenine pathway metabolites (KYN, kynurenic acid KYNA, tryptophan TRP, quinolinic acid QUIN, KYN to TRP ratio) and depression symptoms in...

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Detalhes bibliográficos
Publicado no:Neurosci Biobehav Rev
Main Authors: Hunt, Charlotte, Macedo e Cordeiro, Thiago, Suchting, Robert, de Dios, Constanza, Cuellar Leal, Valeria A., Soares, Jair C, Dantzer, Robert, Teixeira, Antonio, Selvaraj, Sudhakar
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087452/
https://ncbi.nlm.nih.gov/pubmed/32853625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neubiorev.2020.08.010
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