Quantifying noxious-evoked baseline sensitivity in neonates to optimise analgesic trials

Despite the high burden of pain experienced by hospitalised neonates, there are few analgesics with proven efficacy. Testing analgesics in neonates is experimentally and ethically challenging and minimising the number of neonates required to demonstrate efficacy is essential. EEG (electroencephalogr...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Cobo, Maria M, Hartley, Caroline, Gursul, Deniz, Andritsou, Foteini, van der Vaart, Marianne, Schmidt Mellado, Gabriela, Baxter, Luke, Duff, Eugene P, Buckle, Miranda, Evans Fry, Ria, Green, Gabrielle, Hoskin, Amy, Rogers, Richard, Adams, Eleri, Moultrie, Fiona, Slater, Rebeccah
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087440/
https://ncbi.nlm.nih.gov/pubmed/33847561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65266
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