Quantifying noxious-evoked baseline sensitivity in neonates to optimise analgesic trials

Despite the high burden of pain experienced by hospitalised neonates, there are few analgesics with proven efficacy. Testing analgesics in neonates is experimentally and ethically challenging and minimising the number of neonates required to demonstrate efficacy is essential. EEG (electroencephalogr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Cobo, Maria M, Hartley, Caroline, Gursul, Deniz, Andritsou, Foteini, van der Vaart, Marianne, Schmidt Mellado, Gabriela, Baxter, Luke, Duff, Eugene P, Buckle, Miranda, Evans Fry, Ria, Green, Gabrielle, Hoskin, Amy, Rogers, Richard, Adams, Eleri, Moultrie, Fiona, Slater, Rebeccah
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087440/
https://ncbi.nlm.nih.gov/pubmed/33847561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65266
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