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Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers

Restriction of HIV-1 replication in elite controllers (ECs) is frequently attributed to T cell–mediated immune responses, while the specific contribution of innate immune cells is less clear. Here, we demonstrate an upregulation of the host long noncoding RNA (lncRNA) MIR4435-2HG in primary myeloid...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Hartana, Ciputra Adijaya, Rassadkina, Yelizaveta, Gao, Ce, Martin-Gayo, Enrique, Walker, Bruce D., Lichterfeld, Mathias, Yu, Xu G.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087208/
https://ncbi.nlm.nih.gov/pubmed/33938445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI146136
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