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Middle-Down Characterization of the Cell Cycle Dependence of Histone H4 Posttranslational Modifications and Proteoforms

Post-translational modifications (PTMs) of histones are important epigenetic regulatory mechanisms that are often dysregulated in cancer. We employ middle-down proteomics to investigate the PTMs and proteoforms of histone H4 during cell cycle progression. We use pH gradient weak cation exchange-hydr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proteomics
Päätekijät: Jiang, Tingting, Hoover, Michael E., Holt, Matthew V., Freitas, Michael A., Marshall, Alan G., Young, Nicolas L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087174/
https://ncbi.nlm.nih.gov/pubmed/29667342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700442
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