Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events

Homologous recombination (HR) faithfully restores DNA double-strand breaks. Defects in this HR repair pathway are associated with cancer predisposition. In genetic engineering, HR has been used extensively to study gene function and it represents an ideal method of gene therapy for single gene disor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bernardi, Alejandra, Gobelli, Dino, Serna, Julia, Nawrocka, Paulina, March-Rosselló, Gabriel, Orduña, Antonio, Kozlowski, Piotr, Simarro, María, de la Fuente, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087102/
https://ncbi.nlm.nih.gov/pubmed/33930025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237413
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