High molecular weight sodium hyaluronate improves survival of syndecan-1-deficient septic mice by inhibiting neutrophil migration

We investigated the role of endothelial glycocalyx and its component syndecan-1 protein in the pathophysiology of sepsis-induced vascular hyper-permeability and examined the therapeutic effects of high-molecular-weight sodium hyaluronate (HMW-SH). METHODS: Sepsis was induced by cotton smoke inhalati...

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Veröffentlicht in:PLoS One
Hauptverfasser: Baljinnyam, Tuvshintugs, Radnaa, Enkhtuya, Ouellette, Casey M., Nelson, Christina, Niimi, Yosuke, Andersen, Clark R., Popov, Vsevolod, Lee, Jae-Woo, Prough, Donald S., Enkhbaatar, Perenlei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087021/
https://ncbi.nlm.nih.gov/pubmed/33930030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250327
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