A heparin–rosuvastatin-loaded P(LLA-CL) nanofiber-covered stent inhibits inflammatory smooth-muscle cell viability to reduce in-stent stenosis and thrombosis

BACKGROUND: An endovascular covered-stent has unique advantages in treating complex intracranial aneurysms; however, in-stent stenosis and late thrombosis have become the main factors affecting the efficacy of covered-stent treatment. Smooth-muscle-cell phenotypic modulation plays an important role...

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Bibliographische Detailangaben
Veröffentlicht in:J Nanobiotechnology
Hauptverfasser: Liu, Yingjun, Liu, Peixi, Song, Yaying, Li, Sichen, Shi, Yuan, Quan, Kai, Yu, Guo, Li, Peiliang, An, Qingzhu, Zhu, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086342/
https://ncbi.nlm.nih.gov/pubmed/33926468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00867-8
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