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Activation of Notch3 in osteoblasts/osteocytes causes compartment-specific changes in bone remodeling

Notch receptors maintain skeletal homeostasis. NOTCH1 and 2 have been studied for their effects on bone remodeling. Although NOTCH3 plays a significant role in vascular physiology, knowledge about its function in other cellular environments, including bone, is limited. The present study was conducte...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Canalis, Ernesto, Zanotti, Stefano, Schilling, Lauren, Eller, Tabitha, Yu, Jungeun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086145/
https://ncbi.nlm.nih.gov/pubmed/33774049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100583
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