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A novel peptide antagonist of the human growth hormone receptor

Excess circulating human growth hormone (hGH) in vivo is linked to metabolic and growth disorders such as cancer, diabetes, and acromegaly. Consequently, there is considerable interest in developing antagonists of hGH action. Here, we present the design, synthesis, and characterization of a 16-resid...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Basu, Reetobrata, Nahar, Khairun, Kulkarni, Prateek, Kerekes, Olivia, Sattler, Maya, Hall, Zachary, Neggers, Sebastian, Holub, Justin M., Kopchick, John J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086144/
https://ncbi.nlm.nih.gov/pubmed/33774052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100588
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