RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7

Osteoarthritis (OA) is a highly prevalent and debilitating joint disorder that characterized by progressive destruction of articular cartilage. There is no effective disease-modifying therapy for the condition due to limited understanding of the molecular mechanisms on cartilage maintenance and dest...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Autores principales: Cheng, Jin, Duan, Xiaoning, Fu, Xin, Jiang, Yanfang, Yang, Peng, Cao, Chenxi, Li, Qi, Zhang, Jiying, Hu, Xiaoqing, Zhang, Xin, Ao, Yingfang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085605/
https://ncbi.nlm.nih.gov/pubmed/33937236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.638382
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