CD21(lo/−)CD27(−)IgM(−) Double-Negative B Cells Accumulate in the Joints of Patients With Antinuclear Antibody-Positive Juvenile Idiopathic Arthritis

Juvenile idiopathic arthritis (JIA) encompasses a heterogeneous group of diseases. The appearance of antinuclear antibodies (ANAs) in almost half of the patients suggests B cell dysregulation as a distinct pathomechanism in these patients. Additionally, ANAs were considered potential biomarkers enco...

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Bibliografski detalji
Izdano u:Front Pediatr
Glavni autori: Dirks, Johannes, Fischer, Jonas, Haase, Gabriele, Holl-Wieden, Annette, Hofmann, Christine, Girschick, Hermann, Morbach, Henner
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pediatrics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085394/
https://ncbi.nlm.nih.gov/pubmed/33937147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2021.635815
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