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Inhibiting Pyridoxal Kinase of Entamoeba histolytica Is Lethal for This Pathogen
Pyridoxal 5’-phosphate (PLP) functions as a cofactor for hundreds of different enzymes that are crucial to the survival of microorganisms. PLP-dependent enzymes have been extensively characterized and proposed as drug targets in Entamoeba histolytica. This pathogen is unable to synthesize vitamin B(...
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| Vydáno v: | Front Cell Infect Microbiol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085340/ https://ncbi.nlm.nih.gov/pubmed/33937101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.660466 |
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