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Orexinergic descending inhibitory pathway mediates linalool odor-induced analgesia in mice

Linalool odor exposure induces an analgesic effect in mice. This effect disappeared in the anosmic model mice, indicating that olfactory input evoked by linalool odor triggered this effect. Furthermore, hypothalamic orexinergic neurons play a pivotal role in this effect. However, the neuronal circui...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Higa, Yurina, Kashiwadani, Hideki, Sugimura, Mitsutaka, Kuwaki, Tomoyuki
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085205/
https://ncbi.nlm.nih.gov/pubmed/33927235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88359-5
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