KPT-330 Prevents Aortic Valve Calcification via a Novel C/EBPβ Signaling Pathway

RATIONALE. Calcific Aortic Valve Disease (CAVD) affects more than 5.2 million people in the US. The only effective treatment is surgery and this comes with complications and no guarantee of long-term success. OBJECTIVE. Outcomes from pharmacological initiatives remain unsubstantiated and therefore t...

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Publicado en:Circ Res
Autores principales: Dutta, Punashi, Kodigepalli, Karthik M., LaHaye, Stephanie, Thompson, J. Will, Rains, Sarah, Nagel, Casey, Thatcher, Kaitlyn, Hinton, Robert B., Lincoln, Joy
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085092/
https://ncbi.nlm.nih.gov/pubmed/33601919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318503
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