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The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors
The maturation of coronavirus SARS-CoV-2, which is the etiological agent at the origin of the COVID-19 pandemic, requires a main protease M(pro) to cleave the virus-encoded polyproteins. Despite a wealth of experimental information already available, there is wide disagreement about the M(pro) monom...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085067/ https://ncbi.nlm.nih.gov/pubmed/33927258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88630-9 |
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