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Kidney iron deposition by R2* is associated with hemolysis and urinary iron

Kidney iron deposition measured by R2* MRI is posited to result from tubular reabsorption of filtered hemoglobin due to intravascular hemolysis. In chronically transfused sickle cell disease (SCD), R2* is elevated and positively correlated with lactate dehydrogenase (LDH).(1) To account for contribu...

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Détails bibliographiques
Publié dans:Br J Haematol
Auteurs principaux: Denton, Christopher C, Detterich, Jon A, Coates, Thomas D, Wood, John C
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084863/
https://ncbi.nlm.nih.gov/pubmed/33216350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.17085
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